Immunology Group senior scientist 上海

月薪： 1-1.5万/月

该公司所有职位
  • 无工作经验
  • 招若干人
  • 英语良好
  • 02-08 发布
  • 五险一金
  • 免费班车
  • 员工旅游
  • 餐饮补贴
  • 专业培训
  • 年终奖金
  • 股票期权
  • 弹性工作
  • 定期体检

职位描述

岗位职责： You will be responsible for designing, executing and reporting the results of experiments to support projects from target identification and validation through to clinical candidate selection. You will use a wide range of advanced methodologies to probe mechanisms and test drugs, primarily through in vitro and ex vivo cell-based immunological assays. The successful candidate will have excellent oral and written communication skills, work well independently and as part of a team, and be able to execute on multiple projects simultaneously. With limited supervision, the role includes developing and optimizing methodologies and assays and making decisions using good scientific judgment. The position is a hands-on, laboratory based role with no direct reports.   任职资格： Ph.D. in Immunology, cell biology or related field with a minimum of 3 years’ experience in pharmaceutical/biotech industry or in an academic setting.Outstanding candidates with a Master’s degree with a minimum of 7 years’ industry experience will also be consideredSolid training and background in cellular immunology, preferably with expertise in immune-oncology, autoimmunity, and associated rodent pre-clinical models.Ability to independently design, perform and interpret data derived from cellular immune function assays.Broad expertise and familiarity with assays and technologies commonly used to assess immune endpoints (e.g., MLR, antigen-specific T/APC cultures; ELISA/ELISPOT, qPCR); solid cell line and primary immune cell tissue culture skills.Experience in multi-parameter FACS analysis and proficiency in downstream FACS data analysis using FlowJo.Ability to organize and communicate complex data sets in a clear and concise manner to key stakeholders from diverse backgrounds. Basic understanding of statistics, data analysis, and assessment of reproducibility and reliability of experimental data.Ability to contribute at a scientific and strategic level to drug discovery research programs in immunology, including proposal and identification/validation of novel targets.S/he should be a strong team player with excellent oral and written communication skills and a demonstrated ability to work independently to design experiments, generate and interpret data, troubleshoot, and suggest next steps.Demonstrated project lead experience in an academic or industrial research setting.Demonstrated experience mentoring and training junior scientists.Proven experience with biologics drug discovery and demonstrable knowledge of multiple large molecule formats and associated technologies.Experience with in vivo immune-mechanistic or autoimmune/cancer disease models in the mouse system and their application towards pharmacological assessment of drug efficacy and mode-of-action.Demonstrable experience with in vitro pharmacology assays involving large or small molecule drugs, e.g., experimental design and replication, titration and potency value determination, etc. Experience with isolation, characterization, and functional testing of primary human immune cells from healthy donors or disease patient-derived materials.Genetic engineering of reporter cell lines and/or primary cells: molecular biology skills (e.g., plasmid manipulation and transfection, clonal selection) and experience with gene editing technologies (e.g., si/shRNA and CRISPR/Cas9 via transfection or retroviral delivery). 职能类别： 生物工程/生物制药

联系方式

上海市外高桥保税区富特中路288号

公司信息

药明生物（WuXi Biologics）是香港上市公司（代码：2269），我们是全球领先的开放式、一体化生物制药能力和技术平台，旗下包括无锡药明康德生物技术股份有限公司、上海药明生物技术有限公司、苏州药明康德检测检验有限责任公司，并在美国和英国设有子公司。公司为全球生物制药公司和生物技术公司提供全方位的端到端研发服务，帮助任何人、任何公司发现、开发及生产生物药，实现从概念到商业化生产的全过程，加速全球生物药研发进程，降低研发成本，造福病患。目前，公司规模达到2300多人，有200多位拥有海外高等学位和工作经验的海归科学家，拥有丰富的欧美市场抗体开发、生产、质量控制、临床前研究和注册的经验，打造了世界一流的生物药研究、开发及生产团队。 更多信息，请登录公司官网：http://www.wuxibiologics.com.cn/

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